Infected hematopoietic stem cells and with integrated HBV DNA generate defective T cells in chronic HBV infection patients

Infected hematopoietic stem cells and with integrated HBV DNA generate defective T cells in chronic HBV infection patients

A weak T-cell response plays a key role in the persistence of hepatitis B virus (HBV) infection. We aimed to confirm that T-cell defects in patients with chronic HBV infection are associated with HBV DNA infection of bone marrow (BM) hematopoietic stem cells (HSCs). Using reverse transcription polym...

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Bibliographic Details
Main Authors: Shi, Y, Lan, Y, Cao, F, Teng, Y, Li, L, Wang, F, Li, J, Zhou, J, Li, Y
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237112/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237112/

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