Proteasome inhibitor lactacystin enhances cisplatin cytotoxicity by increasing endoplasmic reticulum stress-associated apoptosis in HeLa cells

Cisplatin is commonly used as a therapeutic agent, despite its known adverse side effects and the occurrence of drug resistance. The development of novel methods for combination therapy with cisplatin is required in order to circumvent these limitations of cisplatin alone. The proteasome inhibitor l...

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Bibliographic Details
Main Authors: XU, YE, LI, DI, ZENG, LINCHUAN, WANG, CHUNYAN, ZHANG, LILI, WANG, YAN, YU, YANG, LIU, SHIBING, LI, ZHIXIN
Format: Online
Language:English
Published: D.A. Spandidos 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237085/