A Rat Model of Striatonigral Degeneration Generated by Simultaneous Injection of 6-Hydroxydopamine into the Medial Forebrain Bundle and Quinolinic Acid into the Striatum
A double toxin-double lesion strategy is well-known to generate a rat model of striatonigral degeneration (SND) such as multiple system atrophy-parkinsonian type. However, with this model it is difficult to distinguish SND from Parkinson's disease (PD). In this study, we propose a new rat model...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Korean Academy of Medical Sciences
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234925/ |