Robertsonian translocation between chromosomes (no.21/14) in relation to the history of spontaneous abortion in a family
Background: Approximately 205 million pregnancies occur each year in the worldwide. On the other hand, Spontaneous abortion has been reported in 15-20% of all diagnosed pregnancies. The most common cause of spontaneous abortion is chromosomal abnormalities of the embryo. Robertsonian translocation...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Research and Clinical Center for Infertility
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233318/ |
| Summary: | Background: Approximately 205 million pregnancies occur each year in the worldwide. On the other hand, Spontaneous abortion has been reported in 15-20% of all diagnosed pregnancies. The most common cause of spontaneous abortion is chromosomal abnormalities of the embryo. Robertsonian translocation carriers specially 21-14 are the most common balanced rearrangement among the carrier couples with the history of spontaneous abortion. In order to search for balanced chromosomal rearrangement and cytogenetic disorders, 10 members of related family with consanguinity marriage with the history of recurrent miscarriage were assessed. |
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