In vitro co-culture systems for studying molecular basis of cellular interaction between Aire-expressing medullary thymic epithelial cells and fresh thymocytes
We previously established three mouse cell lines (Aire+TEC1, Aire+TEC2 and Aire+DC) from the medullary thymic epithelial cells (mTECs) and dendritic cells (mDCs). These cells constitutively expressed “autoimmune regulator (Aire) gene” and they exhibited various features of self antigen-presenting ce...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Company of Biologists
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232765/ |