Reduced Expression of the Polymeric Immunoglobulin Receptor in Pancreatic and Periampullary Adenocarcinoma Signifies Tumour Progression and Poor Prognosis

The polymeric immunoglobulin receptor (pIgR) is a key component of the mucosal immune system that mediates epithelial transcytosis of immunoglobulins. High pIgR expression has been reported to correlate with a less aggressive tumour phenotype and an improved prognosis in several human cancer types....

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Bibliographic Details
Main Authors: Fristedt, Richard, Elebro, Jacob, Gaber, Alexander, Jonsson, Liv, Heby, Margareta, Yudina, Yulyana, Nodin, Björn, Uhlén, Mathias, Eberhard, Jakob, Jirström, Karin
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232506/