Promoter Methylation-Mediated Silencing of β-Catenin Enhances Invasiveness of Non-Small Cell Lung Cancer and Predicts Adverse Prognosis

Promoter Methylation-Mediated Silencing of β-Catenin Enhances Invasiveness of Non-Small Cell Lung Cancer and Predicts Adverse Prognosis

β-Catenin plays dual role in adhesion complex formation and the Wnt signaling pathway. Although β-catenin expression appears to be upregulated and Wnt signaling pathway is activated in the majority of cancers, its expression level seems to be lost in non-small cell lung cancer (NSCLC). We previously...

Full description

Bibliographic Details
Main Authors: Miao, Yuan, Wang, Liang, Zhang, Xiupeng, Xu, Xiaohan, Jiang, Guiyang, Fan, Chuifeng, Liu, Yang, Lin, Xuyong, Yu, Juanhan, Zhang, Yong, Wang, Enhua
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232381/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232381/

Similar Items