Brain Metastases of Papillary Thyroid Carcinoma with Horner's Syndrome

Papillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy and has relatively favorable prognosis. Blood-borne metastases of PTC are very rare among the thyroid malignancies. Moreover a case of blood-borne central nervous system metastasized PTC with only unilateral Horner'...

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Main Authors: Cho, Sung-Hoon, Kim, Sang-Hyo, Lee, Jung-Hwan, Joo, Won-Il, Chough, Chung-Kee, Park, Hae-Kwan, Lee, Kyung-Jin, Rha, Hyoung-Kyun
Format: Online
Language:English
Published: The Korean Brain Tumor Society; The Korean Society for Neuro-Oncology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231621/
id pubmed-4231621
recordtype oai_dc
spelling pubmed-42316212014-11-18 Brain Metastases of Papillary Thyroid Carcinoma with Horner's Syndrome Cho, Sung-Hoon Kim, Sang-Hyo Lee, Jung-Hwan Joo, Won-Il Chough, Chung-Kee Park, Hae-Kwan Lee, Kyung-Jin Rha, Hyoung-Kyun Case Report Papillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy and has relatively favorable prognosis. Blood-borne metastases of PTC are very rare among the thyroid malignancies. Moreover a case of blood-borne central nervous system metastasized PTC with only unilateral Horner's syndrome, and without any abnormalities in laboratory or physical examinations has not been described before. A 53-year-old female patient had been managed in ophthalmologic clinic due to vague symptoms of right monocular blurred vision with eye dryness for 3 months, but showed no signs of improvement. So it was performed a magnetic resonance imaging and magnetic resonance angiography to evaluate the possibilities of cerebral lesion. And a left frontal mass was incidentally found, and the tumor turned out to be a PTC that had metastasized to brain, regional lymph node, cervical, thoracic spine, and lung. We describe a PTC with extraordinary initial symptoms that metastasized to an unusual site. We recommend that if a papillary thyroid tumor with unusual symptoms or at an advanced stage is found, further investigation should be performed for distant metastasis. The Korean Brain Tumor Society; The Korean Society for Neuro-Oncology 2014-10 2014-10-31 /pmc/articles/PMC4231621/ /pubmed/25408940 http://dx.doi.org/10.14791/btrt.2014.2.2.132 Text en Copyright © 2014 The Korean Brain Tumor Society and The Korean Society for Neuro-Oncology http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Cho, Sung-Hoon
Kim, Sang-Hyo
Lee, Jung-Hwan
Joo, Won-Il
Chough, Chung-Kee
Park, Hae-Kwan
Lee, Kyung-Jin
Rha, Hyoung-Kyun
spellingShingle Cho, Sung-Hoon
Kim, Sang-Hyo
Lee, Jung-Hwan
Joo, Won-Il
Chough, Chung-Kee
Park, Hae-Kwan
Lee, Kyung-Jin
Rha, Hyoung-Kyun
Brain Metastases of Papillary Thyroid Carcinoma with Horner's Syndrome
author_facet Cho, Sung-Hoon
Kim, Sang-Hyo
Lee, Jung-Hwan
Joo, Won-Il
Chough, Chung-Kee
Park, Hae-Kwan
Lee, Kyung-Jin
Rha, Hyoung-Kyun
author_sort Cho, Sung-Hoon
title Brain Metastases of Papillary Thyroid Carcinoma with Horner's Syndrome
title_short Brain Metastases of Papillary Thyroid Carcinoma with Horner's Syndrome
title_full Brain Metastases of Papillary Thyroid Carcinoma with Horner's Syndrome
title_fullStr Brain Metastases of Papillary Thyroid Carcinoma with Horner's Syndrome
title_full_unstemmed Brain Metastases of Papillary Thyroid Carcinoma with Horner's Syndrome
title_sort brain metastases of papillary thyroid carcinoma with horner's syndrome
description Papillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy and has relatively favorable prognosis. Blood-borne metastases of PTC are very rare among the thyroid malignancies. Moreover a case of blood-borne central nervous system metastasized PTC with only unilateral Horner's syndrome, and without any abnormalities in laboratory or physical examinations has not been described before. A 53-year-old female patient had been managed in ophthalmologic clinic due to vague symptoms of right monocular blurred vision with eye dryness for 3 months, but showed no signs of improvement. So it was performed a magnetic resonance imaging and magnetic resonance angiography to evaluate the possibilities of cerebral lesion. And a left frontal mass was incidentally found, and the tumor turned out to be a PTC that had metastasized to brain, regional lymph node, cervical, thoracic spine, and lung. We describe a PTC with extraordinary initial symptoms that metastasized to an unusual site. We recommend that if a papillary thyroid tumor with unusual symptoms or at an advanced stage is found, further investigation should be performed for distant metastasis.
publisher The Korean Brain Tumor Society; The Korean Society for Neuro-Oncology
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231621/
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