Blocking of integrins inhibits HIV-1 infection of human cervical mucosa immune cells with free and complement-opsonized virions

Blocking of integrins inhibits HIV-1 infection of human cervical mucosa immune cells with free and complement-opsonized virions

The initial interaction between HIV-1 and the host occurs at the mucosa during sexual intercourse. In cervical mucosa, HIV-1 exists both as free and opsonized virions and this might influence initial infection. We used cervical explants to study HIV-1 transmission, the effects of opsonization on inf...

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Bibliographic Details
Main Authors: Tjomsland, Veronica, Ellegård, Rada, Kjölhede, Preben, Wodlin, Ninni Borendal, Hinkula, Jorma, Lifson, Jeffrey D, Larsson, Marie
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231223/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231223/

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