High-Resolution Structure and Mechanism of an F/V-Hybrid Rotor Ring in a Na+-coupled ATP Synthase

All rotary ATPases catalyze the interconversion of ATP and ADP-Pi through a mechanism that is coupled to the transmembrane flow of H+ or Na+. Physiologically, however, F/A-type enzymes specialize in ATP synthesis driven by downhill ion diffusion, while eukaryotic V-type ATPases function as ion pumps...

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Bibliographic Details
Main Authors: Matthies, Doreen, Zhou, Wenchang, Klyszejko, Adriana L., Anselmi, Claudio, Yildiz, Özkan, Brandt, Karsten, Müller, Volker, Faraldo-Gómez, José D., Meier, Thomas
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228694/