SNP-guided identification of monoallelic DNA-methylation events from enrichment-based sequencing data

Monoallelic gene expression is typically initiated early in the development of an organism. Dysregulation of monoallelic gene expression has already been linked to several non-Mendelian inherited genetic disorders. In humans, DNA-methylation is deemed to be an important regulator of monoallelic gene...

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Bibliographic Details
Main Authors: Steyaert, Sandra, Van Criekinge, Wim, De Paepe, Ayla, Denil, Simon, Mensaert, Klaas, Vandepitte, Katrien, Berghe, Wim Vanden, Trooskens, Geert, De Meyer, Tim
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227762/