Why base tautomerization does not cause errors in mRNA decoding on the ribosome

The structure of the genetic code implies strict Watson–Crick base pairing in the first two codon positions, while the third position is known to be degenerate, thus allowing wobble base pairing. Recent crystal structures of near-cognate tRNAs accommodated into the ribosomal A-site, however, show ca...

Full description

Bibliographic Details
Main Authors: Satpati, Priyadarshi, Åqvist, Johan
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227757/