CD40-Mediated Amplification of Local Immunity by Epithelial Cells Is Impaired by HPV

The interaction between the transmembrane glycoprotein surface receptor CD40 expressed by skin epithelial cells (ECs) and its T-cell–expressed ligand CD154 was suggested to exacerbate inflammatory skin diseases. However, the full spectrum of CD40-mediated effects by ECs underlying this observation i...

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Bibliographic Details
Main Authors: Tummers, Bart, Goedemans, Renske, Jha, Veena, Meyers, Craig, Melief, Cornelis J M, van der Burg, Sjoerd H, Boer, Judith M
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227541/