Identifying Genetic Variants for Heart Rate Variability in the Acetylcholine Pathway

Heart rate variability is an important risk factor for cardiovascular disease and all-cause mortality. The acetylcholine pathway plays a key role in explaining heart rate variability in humans. We assessed whether 443 genotyped and imputed common genetic variants in eight key genes (CHAT, SLC18A3, S...

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Bibliographic Details
Main Authors: Riese, Harriëtte, Muñoz, Loretto M., Hartman, Catharina A., Ding, Xiuhua, Su, Shaoyong, Oldehinkel, Albertine J., van Roon, Arie M., van der Most, Peter J., Lefrandt, Joop, Gansevoort, Ron T., van der Harst, Pim, Verweij, Niek, Licht, Carmilla M. M., Boomsma, Dorret I., Hottenga, Jouke-Jan, Willemsen, Gonneke, Penninx, Brenda W. J. H., Nolte, Ilja M., de Geus, Eco J. C., Wang, Xiaoling, Snieder, Harold
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226560/