Interface dynamics explain assembly dependency of influenza neuraminidase catalytic activity
Influenza virus neuraminidase (iNA) is a homotetrameric surface protein of the influenza virus and an established target for antiviral drugs. In contrast to neuraminidases (NAs) of other biological systems (non-iNAs), enzymatic activity of iNA is only observed in a quaternary assembly and iNA needs...
| Main Authors: | , , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Taylor & Francis
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226318/ |