Hypoplastic Left Heart Syndrome – Unresolved Issues

Hypoplastic Left Heart Syndrome – Unresolved Issues

Hypoplastic left heart syndrome (HLHS) is one of the most challenging congenital heart defects. At present, it is expected that – at best – 70% of newborns with HLHS will reach adulthood. This review addresses the problems of right ventricular (RV) failure and insufficient growth of pulmonary vascul...

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Main Authors: Arnold, Raoul Roman, Loukanov, Tsvetomir, Gorenflo, Matthias
Format: Online
Language:English
Published: Frontiers Media S.A. 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225740/
id pubmed-4225740
recordtype oai_dc
spelling pubmed-42257402014-11-25 Hypoplastic Left Heart Syndrome – Unresolved Issues Arnold, Raoul Roman Loukanov, Tsvetomir Gorenflo, Matthias Pediatrics Hypoplastic left heart syndrome (HLHS) is one of the most challenging congenital heart defects. At present, it is expected that – at best – 70% of newborns with HLHS will reach adulthood. This review addresses the problems of right ventricular (RV) failure and insufficient growth of pulmonary vasculature in these patients. In order to further improve long-term prognosis translational research to control RV function, growth of pulmonary arteries and progress in chronic circulatory support are clearly needed to provide a further improvement for adults with HLHS. Frontiers Media S.A. 2014-11-10 /pmc/articles/PMC4225740/ /pubmed/25426478 http://dx.doi.org/10.3389/fped.2014.00125 Text en Copyright © 2014 Arnold, Loukanov and Gorenflo. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Arnold, Raoul Roman
Loukanov, Tsvetomir
Gorenflo, Matthias
spellingShingle Arnold, Raoul Roman
Loukanov, Tsvetomir
Gorenflo, Matthias
Hypoplastic Left Heart Syndrome – Unresolved Issues
author_facet Arnold, Raoul Roman
Loukanov, Tsvetomir
Gorenflo, Matthias
author_sort Arnold, Raoul Roman
title Hypoplastic Left Heart Syndrome – Unresolved Issues
title_short Hypoplastic Left Heart Syndrome – Unresolved Issues
title_full Hypoplastic Left Heart Syndrome – Unresolved Issues
title_fullStr Hypoplastic Left Heart Syndrome – Unresolved Issues
title_full_unstemmed Hypoplastic Left Heart Syndrome – Unresolved Issues
title_sort hypoplastic left heart syndrome – unresolved issues
description Hypoplastic left heart syndrome (HLHS) is one of the most challenging congenital heart defects. At present, it is expected that – at best – 70% of newborns with HLHS will reach adulthood. This review addresses the problems of right ventricular (RV) failure and insufficient growth of pulmonary vasculature in these patients. In order to further improve long-term prognosis translational research to control RV function, growth of pulmonary arteries and progress in chronic circulatory support are clearly needed to provide a further improvement for adults with HLHS.
publisher Frontiers Media S.A.
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225740/
_version_ 1613154312970567680

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