c-Kit Expression is Rate-Limiting for Stem Cell Factor-Mediated Disease Progression in Adenoid Cystic Carcinoma of the Salivary Glands12

Adenoid cystic carcinoma (ACC) is an aggressive malignant neoplasm of the salivary glands in which c-Kit is overexpressed and activated, although the mechanism for this is as yet unclear. We analyzed 27 sporadic ACC tumor specimens to examine the biologic and clinical significance of c-Kit activatio...

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Bibliographic Details
Main Authors: Phuchareon, Janyaporn, van Zante, Annemieke, Overdevest, Jonathan B., McCormick, Frank, Eisele, David W., Tetsu, Osamu
Format: Online
Language:English
Published: Neoplasia Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225653/