Unsupervised Deconvolution of Dynamic Imaging Reveals Intratumor Vascular Heterogeneity and Repopulation Dynamics

With the existence of biologically distinctive malignant cells originated within the same tumor, intratumor functional heterogeneity is present in many cancers and is often manifested by the intermingled vascular compartments with distinct pharmacokinetics. However, intratumor vascular heterogeneity...

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Bibliographic Details
Main Authors: Chen, Li, Choyke, Peter L., Wang, Niya, Clarke, Robert, Bhujwalla, Zaver M., Hillman, Elizabeth M. C., Wang, Ge, Wang, Yue
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224420/