A workflow for the automatic segmentation of organelles in electron microscopy image stacks

Electron microscopy (EM) facilitates analysis of the form, distribution, and functional status of key organelle systems in various pathological processes, including those associated with neurodegenerative disease. Such EM data often provide important new insights into the underlying disease mechanis...

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Bibliographic Details
Main Authors: Perez, Alex J., Seyedhosseini, Mojtaba, Deerinck, Thomas J., Bushong, Eric A., Panda, Satchidananda, Tasdizen, Tolga, Ellisman, Mark H.
Format: Online
Language:English
Published: Frontiers Media S.A. 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224098/