Acquisition of a Quantitative, Stoichiometrically Conserved Ratiometric Marker of Maturation Status in Stem Cell-Derived Cardiac Myocytes

There is no consensus in the stem cell field as to what constitutes the mature cardiac myocyte. Thus, helping formalize a molecular signature for cardiac myocyte maturation would advance the field. In the mammalian heart, inactivation of the “fetal” TNNI gene, TNNI1 (ssTnI), together in temporal con...

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Bibliographic Details
Main Authors: Bedada, Fikru B., Chan, Sunny S-K., Metzger, Stefania K., Zhang, Liying, Zhang, Jianyi, Garry, Daniel J., Kamp, Timothy J., Kyba, Michael, Metzger, Joseph M.
Format: Online
Language:English
Published: Elsevier 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223713/