Calreticulin Mutations in Myeloproliferative Neoplasms

With the discovery of the JAK2V617F mutation in patients with Philadelphia chromosome-negative (Ph−) myeloproliferative neoplasms (MPNs) in 2005, major advances have been made in the diagnosis of MPNs, in understanding of their pathogenesis involving the JAK/STAT pathway, and finally in the developm...

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Bibliographic Details
Main Author: Lavi, Noa
Format: Online
Language:English
Published: Rambam Health Care Campus 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222424/