Oligonucleotide Aptamers: New Tools for Targeted Cancer Therapy

Aptamers are a class of small nucleic acid ligands that are composed of RNA or single-stranded DNA oligonucleotides and have high specificity and affinity for their targets. Similar to antibodies, aptamers interact with their targets by recognizing a specific three-dimensional structure and are thus...

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Bibliographic Details
Main Authors: Sun, Hongguang, Zhu, Xun, Lu, Patrick Y, Rosato, Roberto R, Tan, Wen, Zu, Youli
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221593/