Spinal fMRI Reveals Decreased Descending Inhibition during Secondary Mechanical Hyperalgesia

Mechanical hyperalgesia is one distressing symptom of neuropathic pain which is explained by central sensitization of the nociceptive system. This sensitization can be induced experimentally with the heat/capsaicin sensitization model. The aim was to investigate and compare spinal and supraspinal ac...

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Bibliographic Details
Main Authors: Rempe, Torge, Wolff, Stephan, Riedel, Christian, Baron, Ralf, Stroman, Patrick W., Jansen, Olav, Gierthmühlen, Janne
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221460/