Quantitative method for the assignment of hinge and shear mechanism in protein domain movements

Motivation: A popular method for classification of protein domain movements apportions them into two main types: those with a ‘hinge’ mechanism and those with a ‘shear’ mechanism. The intuitive assignment of domain movements to these classes has limited the number of domain movements that can be cla...

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Main Authors: Taylor, Daniel, Cawley, Gavin, Hayward, Steven
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221117/
id pubmed-4221117
recordtype oai_dc
spelling pubmed-42211172014-11-10 Quantitative method for the assignment of hinge and shear mechanism in protein domain movements Taylor, Daniel Cawley, Gavin Hayward, Steven Original Papers Motivation: A popular method for classification of protein domain movements apportions them into two main types: those with a ‘hinge’ mechanism and those with a ‘shear’ mechanism. The intuitive assignment of domain movements to these classes has limited the number of domain movements that can be classified in this way. Furthermore, whether intended or not, the term ‘shear’ is often interpreted to mean a relative translation of the domains. Oxford University Press 2014-11-15 2014-07-30 /pmc/articles/PMC4221117/ /pubmed/25078396 http://dx.doi.org/10.1093/bioinformatics/btu506 Text en © The Author 2014. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Taylor, Daniel
Cawley, Gavin
Hayward, Steven
spellingShingle Taylor, Daniel
Cawley, Gavin
Hayward, Steven
Quantitative method for the assignment of hinge and shear mechanism in protein domain movements
author_facet Taylor, Daniel
Cawley, Gavin
Hayward, Steven
author_sort Taylor, Daniel
title Quantitative method for the assignment of hinge and shear mechanism in protein domain movements
title_short Quantitative method for the assignment of hinge and shear mechanism in protein domain movements
title_full Quantitative method for the assignment of hinge and shear mechanism in protein domain movements
title_fullStr Quantitative method for the assignment of hinge and shear mechanism in protein domain movements
title_full_unstemmed Quantitative method for the assignment of hinge and shear mechanism in protein domain movements
title_sort quantitative method for the assignment of hinge and shear mechanism in protein domain movements
description Motivation: A popular method for classification of protein domain movements apportions them into two main types: those with a ‘hinge’ mechanism and those with a ‘shear’ mechanism. The intuitive assignment of domain movements to these classes has limited the number of domain movements that can be classified in this way. Furthermore, whether intended or not, the term ‘shear’ is often interpreted to mean a relative translation of the domains.
publisher Oxford University Press
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221117/
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