Multiple roles for NaV1.9 in the activation of visceral afferents by noxious inflammatory, mechanical, and human disease–derived stimuli

NaV1.9 regulates normal colonic afferent mechanosensation and is required for hypersensitivity to noxious inflammatory mediators and those derived from inflammatory bowel disease tissues.

Bibliographic Details
Main Authors: Hockley, James R.F., Boundouki, George, Cibert-Goton, Vincent, McGuire, Cian, Yip, Ping K., Chan, Christopher, Tranter, Michael, Wood, John N., Nassar, Mohammed A., Blackshaw, L. Ashley, Aziz, Qasim, Michael, Gregory J., Baker, Mark D., Winchester, Wendy J., Knowles, Charles H., Bulmer, David C.
Format: Online
Language:English
Published: Lippincott Williams & Wilkins 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220011/