CARD14 Expression in Dermal Endothelial Cells in Psoriasis

Mutations in the caspase recruitment domain, family member 14 (CARD14) gene have recently been described in psoriasis patients, and explain the psoriasis susceptibility locus 2 (PSORS2). CARD14 is a scaffolding protein that regulates NF-κB activation, and psoriasis-associated CARD14 mutations lead t...

Full description

Bibliographic Details
Main Authors: Harden, Jamie L., Lewis, Steven M., Pierson, Katherine C., Suárez-Fariñas, Mayte, Lentini, Tim, Ortenzio, Francesca S., Zaba, Lisa C., Goldbach-Mansky, Raphaela, Bowcock, Anne M., Lowes, Michelle A.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219711/