Protection of Armadillo/β-Catenin by Armless, a Novel Positive Regulator of Wingless Signaling

This study uses an RNAi screen in Drosophila to identify a UBX protein, Armless, as a novel positive regulator of the important Wingless/Wnt signaling pathway, acting to stabilize Armadillo/?-Catenin by antagonizing its turnover.

Bibliographic Details
Main Authors: Reim, Gerlinde, Hruzova, Martina, Goetze, Sandra, Basler, Konrad
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219662/