Diffusion approximation-based simulation of stochastic ion channels: which method to use?

To study the effects of stochastic ion channel fluctuations on neural dynamics, several numerical implementation methods have been proposed. Gillespie's method for Markov Chains (MC) simulation is highly accurate, yet it becomes computationally intensive in the regime of a high number of channe...

Full description

Bibliographic Details
Main Authors: Pezo, Danilo, Soudry, Daniel, Orio, Patricio
Format: Online
Language:English
Published: Frontiers Media S.A. 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217484/