The monocyte-macrophage axis in the intestine

•Mϕ are involved in gut homeostasis and the pathogenesis of intestinal inflammation.•Resident and proinflammatory intestinal Mϕ both derive from Ly6Chi blood monocytes.•Local environmental factors guide monocyte differentiation in the gut mucosa.•Monocyte differentiation is disrupted by inflammation...

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Bibliographic Details
Main Authors: Bain, Calum C., Mowat, Allan McI
Format: Online
Language:English
Published: Academic Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217150/