Generation of Atoh1-rtTA transgenic mice: a tool for inducible gene expression in hair cells of the inner ear
Atoh1 is a basic helix-loop-helix transcription factor that controls differentiation of hair cells (HCs) in the inner ear and its enhancer region has been used to create several HC-specific mouse lines. We generated a transgenic tetracycline-inducible mouse line (called Atoh1-rtTA) using the Atoh1 e...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217099/ |