G protein-coupled receptors: computer-aided ligand discovery and computational structural analyses in the 2010s

G protein-coupled receptors, or GPCRs, are a large superfamily of proteins found on the plasma membrane of cells. They are involved in most physiological and pathophysiological functions and constitute the target of the majority of marketed drugs. Although these receptors have been historically elus...

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Bibliographic Details
Main Author: Costanzi, Stefano
Format: Online
Language:English
Published: Springer Berlin Heidelberg 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215811/