MRI correlates of disability progression in patients with CIS over 48 months

•We examined 210 clinically isolated syndrome patients on interferon beta.•MRI and clinical assessments were performed at 0, 6, 12, 24, 36 and 48 months.•15.2% of patients developed disability progression and 53.3 % converted to MS.•Gray matter atrophy was strongly associated with sustained disabili...

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Bibliographic Details
Main Authors: Uher, Tomas, Horakova, Dana, Bergsland, Niels, Tyblova, Michaela, Ramasamy, Deepa P., Seidl, Zdenek, Vaneckova, Manuela, Krasensky, Jan, Havrdova, Eva, Zivadinov, Robert
Format: Online
Language:English
Published: Elsevier 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215387/