PKCβ Positively Regulates RANKL-Induced Osteoclastogenesis by Inactivating GSK-3β

Protein kinase C (PKC) family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. However, the role of PKC in receptor activator of NF-κB ligand (RANKL) signaling has remained elusive. We now demonstrate that PKCβ acts as a pos...

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Bibliographic Details
Main Authors: Shin, Jihye, Jang, Hyunduk, Lin, Jingjing, Lee, Soo Young
Format: Online
Language:English
Published: Korean Society for Molecular and Cellular Biology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213766/