KSHV miRNAs Decrease Expression of Lytic Genes in Latently Infected PEL and Endothelial Cells by Targeting Host Transcription Factors

KSHV miRNAs Decrease Expression of Lytic Genes in Latently Infected PEL and Endothelial Cells by Targeting Host Transcription Factors

Kaposi’s sarcoma-associated herpesvirus (KSHV) microRNAs are encoded in the latency-associated region. Knockdown of KSHV miR-K12-3 and miR-K12-11 increased expression of lytic genes in BC-3 cells, and increased virus production from latently infected BCBL-1 cells. Furthermore, iSLK cells infected wi...

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Bibliographic Details
Main Authors: Plaisance-Bonstaff, Karlie, Choi, Hong Seok, Beals, Tyler, Krueger, Brian J., Boss, Isaac W., Gay, Lauren A., Haecker, Irina, Hu, Jianhong, Renne, Rolf
Format: Online
Language:English
Published: MDPI 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213575/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213575/

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