A Comprehensive Comparison of Normalization Methods for Loading Control and Variance Stabilization of Reverse-Phase Protein Array Data

Loading control (LC) and variance stabilization of reverse-phase protein array (RPPA) data have been challenging mainly due to the small number of proteins in an experiment and the lack of reliable inherent control markers. In this study, we compare eight different normalization methods for LC and v...

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Bibliographic Details
Main Authors: Liu, Wenbin, Ju, Zhenlin, Lu, Yiling, Mills, Gordon B, Akbani, Rehan
Format: Online
Language:English
Published: Libertas Academica 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213190/