5-aminoimidazole-4-carboxamide Riboside Induces Apoptosis Through AMP-activated Protein Kinase-independent and NADPH Oxidase-dependent Pathways
It is debatable whether AMP-activated protein kinase (AMPK) activation is involved in anti-apoptotic or pro-apoptotic signaling. AICAR treatment increases AMPK-α1 phosphorylation, decreases intracellular reactive oxygen species (ROS) levels, and significantly increases Annexin V-positive cells, DNA...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
The Korean Association of Immunologists
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212085/ |