A3 Adenosine Receptor Allosteric Modulator Induces an Anti-Inflammatory Effect: In Vivo Studies and Molecular Mechanism of Action

A3 Adenosine Receptor Allosteric Modulator Induces an Anti-Inflammatory Effect: In Vivo Studies and Molecular Mechanism of Action

The A3 adenosine receptor (A3AR) is overexpressed in inflammatory cells and in the peripheral blood mononuclear cells of individuals with inflammatory conditions. Agonists to the A3AR are known to induce specific anti-inflammatory effects upon chronic treatment. LUF6000 is an allosteric compound kno...

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Bibliographic Details
Main Authors: Cohen, Shira, Barer, Faina, Bar-Yehuda, Sara, IJzerman, Adriaan P., Jacobson, Kenneth A., Fishman, Pnina
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211160/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211160/

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