Mice Lacking the Circadian Modulators SHARP1 and SHARP2 Display Altered Sleep and Mixed State Endophenotypes of Psychiatric Disorders

Mice Lacking the Circadian Modulators SHARP1 and SHARP2 Display Altered Sleep and Mixed State Endophenotypes of Psychiatric Disorders

Increasing evidence suggests that clock genes may be implicated in a spectrum of psychiatric diseases, including sleep and mood related disorders as well as schizophrenia. The bHLH transcription factors SHARP1/DEC2/BHLHE41 and SHARP2/DEC1/BHLHE40 are modulators of the circadian system and SHARP1/DEC...

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Bibliographic Details
Main Authors: Baier, Paul C., Brzózka, Magdalena M., Shahmoradi, Ali, Reinecke, Lisa, Kroos, Christina, Wichert, Sven P., Oster, Henrik, Wehr, Michael C., Taneja, Reshma, Hirrlinger, Johannes, Rossner, Moritz J.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207740/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207740/

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