A Palindromic Motif in the −2084 to −2078 Upstream Region is Essential for ABCA12 Promoter Function in Cultured Human Keratinocytes

A Palindromic Motif in the −2084 to −2078 Upstream Region is Essential for ABCA12 Promoter Function in Cultured Human Keratinocytes

ATP-binding cassette transporter family A member 12 (ABCA12) is a keratinocyte transmembrane lipid transporter that plays a critical role in preserving the skin permeability barrier. Biallelic loss of function of the ABCA12 gene is causative of some forms of recessive congenital ichthyosis, an intra...

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Bibliographic Details
Main Authors: Shimizu, Yoshitaka, Ogawa, Yasushi, Sugiura, Kazumitsu, Takeda, Jun-ichi, Sakai-Sawada, Kaori, Yanagi, Teruki, Kon, Atsushi, Sawamura, Daisuke, Shimizu, Hiroshi, Akiyama, Masashi
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206840/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206840/

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