Poly (ADP-ribose) in the pathogenesis of Parkinson's disease

The defining feature of Parkinson’s disease is a progressive and selective demise of dopaminergic neurons. A recent report on Parkinson’s disease animal model demonstrates that poly (ADP-ribose) (PAR) dependent cell death, also named parthanatos, is accountable for selective dopaminergic neuronal lo...

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Bibliographic Details
Main Authors: Lee, Yunjong, Kang, Ho Chul, Lee, Byoung Dae, Lee, Yun-Il, Kim, Young Pil, Shin, Joo-Ho
Format: Online
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206713/