Presynaptic Localization of Smn and hnRNP R in Axon Terminals of Embryonic and Postnatal Mouse Motoneurons

Presynaptic Localization of Smn and hnRNP R in Axon Terminals of Embryonic and Postnatal Mouse Motoneurons

Spinal muscular atrophy (SMA) is caused by deficiency of the ubiquitously expressed survival motoneuron (SMN) protein. SMN is crucial component of a complex for the assembly of spliceosomal small nuclear ribonucleoprotein (snRNP) particles. Other cellular functions of SMN are less characterized so f...

Full description

Bibliographic Details
Main Authors:	Dombert, Benjamin, Sivadasan, Rajeeve, Simon, Christian M., Jablonka, Sibylle, Sendtner, Michael
Format:	Online
Language:	English
Published:	Public Library of Science 2014
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206449/

Similar Items

hnRNP A1 and hnRNP F Modulate the Alternative Splicing of Exon 11 of the Insulin Receptor Gene
by: Talukdar, Indrani, et al.
Published: (2011)

Paralogs hnRNP L and hnRNP LL Exhibit Overlapping but Distinct RNA Binding Constraints
by: Smith, Sarah A., et al.
Published: (2013)

HnRNP-like proteins as post-transcriptional regulators
by: Yeap, Wan Chin, et al.
Published: (2014)

The hnRNP family: insights into their role in health and disease
by: Geuens, Thomas, et al.
Published: (2016)

Characterization of the RNA recognition mode of hnRNP G extends its role in SMN2 splicing regulation
by: Moursy, Ahmed, et al.
Published: (2014)

Smn, the spinal muscular atrophy–determining gene product, modulates axon growth and localization of β-actin mRNA in growth cones of motoneurons
by: Rossoll, Wilfried, et al.
Published: (2003)

Intronic Binding Sites for hnRNP A/B and hnRNP F/H Proteins Stimulate Pre-mRNA Splicing
by: Martinez-Contreras, Rebeca, et al.
Published: (2006)

HnRNP L and hnRNP LL antagonistically modulate PTB-mediated splicing suppression of CHRNA1 pre-mRNA
by: Rahman, Mohammad Alinoor, et al.
Published: (2013)

Lectin-based Isolation and Culture of Mouse Embryonic Motoneurons
by: Conrad, Rebecca, et al.
Published: (2011)

Association of individual hnRNP proteins and snRNPs with nascent transcripts
Published: (1993)

Upregulation of UCP2 by Adiponectin: The Involvement of Mitochondrial Superoxide and hnRNP K
by: Zhou, Mingyan, et al.
Published: (2012)

A nuclear localization domain in the hnRNP A1 protein
Published: (1995)

Distribution studies on polytene chromosomes using antibodies directed against hnRNP
Published: (1981)

AUF1/hnRNP D represses expression of VEGF in macrophages
by: Fellows, Abigail, et al.
Published: (2012)

Caspase-3 cleaves hnRNP K in erythroid differentiation
by: Naarmann-de Vries, I S, et al.
Published: (2013)

TERRA, hnRNP A1, and DNA-PKcs Interactions at Human Telomeres
by: Le, Phuong N., et al.
Published: (2013)

hnRNP A1: The Swiss Army Knife of Gene Expression
by: Jean-Philippe, Jacques, et al.
Published: (2013)

Phosphorylation of hnRNP K controls cytosolic accumulation of TDP-43
by: White, Anthony, et al.
Published: (2013)

hnRNP F Complexes with Tristetraprolin and Stimulates ARE-mRNA Decay
by: Reznik, Boris, et al.
Published: (2014)

The hnRNP-Q Protein LIF2 Participates in the Plant Immune Response
by: Le Roux, Clémentine, et al.
Published: (2014)

Regulation of tyrosine hydroxylase transcription by hnRNP K and DNA secondary structure
by: Banerjee, Kasturi, et al.
Published: (2014)

Identification and characterization of an hnRNP E1 translational silencing motif
by: Brown, Andrew S., et al.
Published: (2016)

hnRNP-Q1 represses nascent axon growth in cortical neurons by inhibiting Gap-43 mRNA translation
by: Williams, Kathryn R., et al.
Published: (2016)

Defective Ca2+ channel clustering in axon terminals disturbs excitability in motoneurons in spinal muscular atrophy
by: Jablonka, Sibylle, et al.
Published: (2007)

Correction: hnRNP K Coordinates Transcriptional Silencing by SETDB1 in Embryonic Stem Cells
by: Thompson, Peter J., et al.
Published: (2016)

hnRNP K Coordinates Transcriptional Silencing by SETDB1 in Embryonic Stem Cells
by: Thompson, Peter J., et al.
Published: (2015)

HuR-Regulated mRNAs Associated with Nuclear hnRNP A1-RNP Complexes
by: Papadodima, Olga, et al.
Published: (2013)

Suppression of HPV-16 late L1 5′-splice site SD3632 by binding of hnRNP D proteins and hnRNP A2/B1 to upstream AUAGUA RNA motifs
by: Li, Xiaoze, et al.
Published: (2013)

Systematic Analysis of Gene Expression Profiles Controlled by hnRNP Q and hnRNP R, Two Closely Related Human RNA Binding Proteins Implicated in mRNA Processing Mechanisms
by: Sara Cappelli, et al.
Published: (2018-08-01)

HnRNP C, YB-1 and hnRNP L coordinately enhance skipping of human MUSK exon 10 to generate a Wnt-insensitive MuSK isoform
by: Nasrin, Farhana, et al.
Published: (2014)

Transcriptional enhancement of Smn levels in motoneurons is crucial for proper axon morphology in zebrafish
by: Spiró, Zoltán, et al.
Published: (2016)

Cell-autonomous axon growth of young motoneurons is triggered by a voltage-gated sodium channel
by: Wetzel, Andrea, et al.
Published: (2013)

Balbiani ring hnRNP substructure visualized by selective staining and electron spectroscopic imaging
Published: (1992)

Spatial code recognition in neuronal RNA targeting: Role of RNA–hnRNP A2 interactions
by: Muslimov, Ilham A., et al.
Published: (2011)

hnRNP A2, a potential ssDNA/RNA molecular adapter at the telomere
by: Moran-Jones, Kim, et al.
Published: (2005)

Host Heterogeneous Ribonucleoprotein K (hnRNP K) as a Potential Target to Suppress Hepatitis B Virus Replication
by: Ng, Lisa F. P, et al.
Published: (2005)

Critical role of hnRNP A1 in HTLV-1 replication in human transformed T lymphocytes
by: Kress, Elsa, et al.
Published: (2005)

hnRNP E1 and E2 have distinct roles in modulating HIV-1 gene expression
by: Woolaway, Kathryn, et al.
Published: (2007)

A Role for the M9 Transport Signal of hnRNP A1 in mRNA Nuclear Export
by: Izaurralde, Elisa, et al.
Published: (1997)

Differential effects of hnRNP D/AUF1 isoforms on HIV-1 gene expression
by: Lund, Nicole, et al.
Published: (2012)