LOS oligosaccharide modification enhances dendritic cell responses to meningococcal native outer membrane vesicles expressing a non-toxic lipid A

Outer membrane vesicles (OMV) are released by many bacteria, and contain immunogenic antigens in addition to harmful inflammatory factors, like lipopolysaccharides. Chemically detoxified OMV have been used in vaccines against Neisseria meningitidis (Nm); however, little is known about their interact...

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Bibliographic Details
Main Authors: Jones, Hannah E, Copland, Alastair, Hamstra, Hendrik Jan, Cohen, Jonathan, Brown, Jeremy, Klein, Nigel, van der Ley, Peter, Dixon, Garth
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204155/