Murine animal models for preclinical islet transplantation: No model fits all (research purposes)

Advances in islet transplantation research have led to remarkable improvements in the outcome in humans with type 1 diabetes. However, pitfalls, mainly linked both to early liver-specific inflammatory events and to pre-existing and transplant-induced auto- and allo-specific adaptive immune responses...

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Bibliographic Details
Main Authors: Cantarelli, Elisa, Citro, Antonio, Marzorati, Simona, Melzi, Raffaella, Scavini, Marina, Piemonti, Lorenzo
Format: Online
Language:English
Published: Landes Bioscience 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204022/