microRNA-mediated regulation of mTOR complex components facilitates discrimination between activation and anergy in CD4 T cells

Using Dicer-deficient CD4 T cells, Marcais et al. show that microRNAs regulate the expression of mTOR components that are needed to discriminate between activating and anergy-inducing stimuli.

Bibliographic Details
Main Authors: Marcais, Antoine, Blevins, Rory, Graumann, Johannes, Feytout, Amelie, Dharmalingam, Gopuraja, Carroll, Thomas, Amado, Inês F., Bruno, Ludovica, Lee, Keunwook, Walzer, Thierry, Mann, Matthias, Freitas, Antonio A., Boothby, Mark, Fisher, Amanda G., Merkenschlager, Matthias
Format: Online
Language:English
Published: The Rockefeller University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203951/