The “Genomic Storm” Induced by Bacterial Endotoxin Is Calmed by a Nuclear Transport Modifier That Attenuates Localized and Systemic Inflammation

The “Genomic Storm” Induced by Bacterial Endotoxin Is Calmed by a Nuclear Transport Modifier That Attenuates Localized and Systemic Inflammation

Lipopolysaccharide (LPS) is a potent microbial virulence factor that can trigger production of proinflammatory mediators involved in the pathogenesis of localized and systemic inflammation. Importantly, the role of nuclear transport of stress responsive transcription factors in this LPS-generated “g...

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Bibliographic Details
Main Authors: DiGiandomenico, Antonio, Veach, Ruth Ann, Zienkiewicz, Jozef, Moore, Daniel J., Wylezinski, Lukasz S., Hutchens, Martha A., Hawiger, Jacek
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203769/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203769/

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