FGF23 regulates renal sodium handling and blood pressure

Fibroblast growth factor-23 (FGF23) is a bone-derived hormone regulating renal phosphate reabsorption and vitamin D synthesis in renal proximal tubules. Here, we show that FGF23 directly regulates the membrane abundance of the Na+:Cl− co-transporter NCC in distal renal tubules by a signaling mechani...

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Bibliographic Details
Main Authors: Andrukhova, Olena, Slavic, Svetlana, Smorodchenko, Alina, Zeitz, Ute, Shalhoub, Victoria, Lanske, Beate, Pohl, Elena E, Erben, Reinhold G
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203353/