Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3

Nutrient availability is the major regulator of life and reproduction, and a complex cellular signaling network has evolved to adapt organisms to fasting. These sensor pathways monitor cellular energy metabolism, especially mitochondrial ATP production and NAD+/NADH ratio, as major signals for nutri...

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Bibliographic Details
Main Authors: Khan, Nahid A, Auranen, Mari, Paetau, Ilse, Pirinen, Eija, Euro, Liliya, Forsström, Saara, Pasila, Lotta, Velagapudi, Vidya, Carroll, Christopher J, Auwerx, Johan, Suomalainen, Anu
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203351/