Interferon-β inhibits glioma angiogenesis through downregulation of vascular endothelial growth factor and upregulation of interferon inducible protein 10
Interferon-β (IFN-β) has been used clinically for malignant glioma growth inhibition. Recently IFN-β is re-evaluated for its sensitization mechanism to the chemotherapeutic agent temozolomide, because angiogenesis is essential for malignant glioma growth. In this study, we investigated new mechanism...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
D.A. Spandidos
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203325/ |