THDP17 Decreases Ammonia Production through Glutaminase Inhibition. A New Drug for Hepatic Encephalopathy Therapy

THDP17 Decreases Ammonia Production through Glutaminase Inhibition. A New Drug for Hepatic Encephalopathy Therapy

Ammonia production is implicated in the pathogenesis of hepatic encephalopathy (HE), being intestinal glutaminase activity the main source for ammonia. Management of ammonia formation can be effective in HE treatment by lowering intestinal ammonia production. The use of glutaminase inhibitors repres...

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Bibliographic Details
Main Authors: Díaz-Herrero, M. Mar, del Campo, José A., Carbonero-Aguilar, Pilar, Vega-Pérez, José M., Iglesias-Guerra, Fernando, Periñán, Ignacio, Miñano, Francisco J., Bautista, Juan, Romero-Gómez, Manuel
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201470/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201470/

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