Novel Sustained-Release of Propafenone through Pellets: Preparation and in Vitro/in Vivo Evaluation

In this study, an extrusion-spheronization method was applied successfully to fabricate propafenone hydrochloride (PPF) sustained-release pellets. Using scanning electron microscopy, it was shown that the PPF pellets had a mean size of approximately 950 µm with a spherical shape. The in vitro releas...

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Bibliographic Details
Main Authors: Zhang, Li, Jiang, Ping, Liu, Ji
Format: Online
Language:English
Published: MDPI 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200845/